ACIP Backs Influenza and COVID Vaccine Co-Administration

Influenza vaccines can be co-administered with COVID-19 vaccines for both kids and grownups, according to upgraded suggestions from the CDC’s Advisory Committee on Immunization Practices (ACIP).

In a consentaneous 14 -0 vote on Thursday, the committee authorized language for co-administration of influenza and COVID-19 vaccines, in line with existing CDC assistance that states COVID-19 vaccines can be administered with other vaccines, though suppliers need to know increased reactogenicity.

Some ACIP members disagreed with the absence of information on co-administration in kids, though CDC personnel kept in mind there had actually been one pre-print analyzing co-administration of influenza vaccine and the Novavax COVID-19 vaccine that revealed no modifications in antibody titers for influenza vaccine and no security concerns.

ACIP member Matthew Daley, MD, of Kaiser Permanente Colorado, motivated extra research study about co-administration of COVID-19 and influenza vaccines, particularly in kids and teenagers.

” Many teenagers will be immunized [against] COVID-19 in the summertime and have their influenza vaccination in the fall” this year, however this might end up being a concern with COVID-19 boosters administered at the very same time as influenza vaccine next year, he stated.

Other modifications to the phrasing of scientific assistance consisted of a more specific declaration about timing of influenza vaccines, stating non-pregnant grownups must prevent influenza vaccine in July and August unless they can not be immunized later on, due to issues about subsiding resistance.

The language likewise stated kids ought to be immunized by the end of October, and pregnant ladies ought to be immunized in the 3rd trimester as quickly as a vaccine appears.

Language about serious allergies was upgraded to more carefully balance with influenza vaccine product packaging, and age signs for cell-based vaccine Flucelvax Quadrivalent were upgraded, as the vaccine is now suggested for people ages 2 and older.

Dengue Vaccine for Kid in Endemic Locations

The committee likewise voted 14 -0 to advise the dengue vaccine for seropositive kids ages 9 to 16 living in dengue endemic locations of the U.S., such as Puerto Rico. The vaccine was authorized for this population in 2019.

CDC personnel highlighted the significance of a laboratory-confirmed favorable test, suggesting previous infection, and worried the requirement for extremely delicate and particular screening prior to vaccination.

One choice was to advise the vaccine through shared medical decision-making, however CDC personnel kept in mind insurer in the impacted locations stated if that held true, moms and dads would need to spend for the test upfront and after that send for compensation.

Provided logistical obstacles, intermediary member Yvonne Maldonado, MD, of the American Academy of Pediatrics (AAP), alerted that even with a complete suggestion, this would not be an “simple procedure,” however that the AAP prepared to engage its regional chapters to get included, along with essential public health stakeholders.

” The threats are very workable, albeit there will be a variety of administrative challenges to move through,” she stated, stating the crucial problems are the “persistence on having an extremely delicate [lab] test offered and the suggestion to just immunize those kids.”

The dengue vaccine is a three-dose vaccine, administered 6 months apart for kids ages 9 to 16 with lab verification of previous dengue infection just.

Two-Dose Rabies Vaccine OKAY ‘d for Kids

In another 14 -0 vote, the committee advised a two-dose rabies vaccine for kids more youthful than age 18 as pre-exposure prophylaxis if they are taking a trip to a nation with prospective rabies direct exposure.

For kids with a “continual and raised threat” of rabies direct exposure, they can either have their titers examined 1 to 3 years later on, and be improved appropriately, or get a booster after day 21 or no behind 3 years after the 2nd shot.

CDC personnel kept in mind that a much shorter vaccination series would be “much easier to execute prior to travel,” though they warned there is no information on this vaccine in kids beyond 3 years.

Formerly, rabies pre-exposure prophylaxis was a three-dose rabies vaccine, however the committee enacted May for the two-dose series in grownups who are suggested for rabies vaccine. The vaccine is to be administered on days 0 and 7.

All 3 votes on influenza vaccine, dengue vaccine, and rabies vaccine were likewise all authorized for their particular Vaccines for Kid resolutions.

As constantly, suggestions of the ACIP are ruled out last up until they are released in the Morbidity and Death Weekly Report

Last Upgraded June 25, 2021

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  Molly Walker is deputy handling editor and covers transmittable illness for MedPage Today. She is a 2020 J2 Accomplishment Award winner for her COVID-19 protection. Follow

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