Comorbidities such as heart problem, breathing disease, kidney illness and cancer result in an increased risk of death from Covid-19 according to new research from the University of East Anglia (UEA) and the Norfolk and Norwich University Hospital (NNUH).
At the start of the pandemic, there was issue that specific medications for hypertension could be linked with even worse outcomes for Covid-19 clients.
Previous research study from the UEA team showed this wasn’t the case which medications for high blood pressure could, in truth, improve Covid-19 survival rates and lower the seriousness of infection.
Brand-new findings, released today in the Journal of the American Medical Association (JAMA) Network Open, additionally reveal that it is comorbidities such as cardiovascular disease, breathing illness, kidney disease, cancer, obesity and increasing age– and having more than one disease or chronic condition at the very same time– that result in increased death and seriousness of disease.
The group reviewed 52 different studies including over 100,000 patients in this, the most comprehensive research study of its kind to date.
They studied the results for patients taking antihypertensives– looking especially at ‘critical’ outcomes such as being confessed to intensive care or being put on a ventilator, and death.
Their meta analysis revealed a significantly lower threat of hospitalisation or death for people taking high blood pressure medications Angiotensin-Converting Enzyme inhibitors (ACEi) or Angiotensin Receptor Blockers (ARB).
However they also found that threats for hospitalisation and death were much greater for people with comorbidities.
Lead scientist Dr Vassilios Vassiliou, from UEA’s Norwich Medical School and Honorary Consultant Cardiologist at NNUH, said: “What a meta analysis provides us is the really big picture.
” With these increased numbers, what we can see extremely clearly now, is that it is the comorbidities such as heart disease or breathing disease, cancer or obesity amongst others that result in an increased death.
” And we can confirm that the high blood pressure medications themselves are protective– not just for individuals who have hypertension, but for individuals with a series of other comorbidities as well,” he added.
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